Welcome to BASP -
Danish National Research
and Novo Nordisk Foundations
Centre for Bacterial Stress Response and Persistence
The aim of the center is to study basic bacterial survival mechanisms.
Bacteria respond to environmental stress by reprogramming their metabolism from rapid to slow growth, a global physiological resetting allowing them to withstand the challenges. Bacteria can thereby enter a state of low metabolic activity called persistence in which they are tolerant to otherwise deadly assaults, including antibiotics. Persistence is a highly understudied phenomenon largely due to technical challenges in studying bacteria at the level of single cells. The outcome of this basic research program will greatly increase our understanding of bacterial survival mechanisms and may, in the future, improve biotechnological processes and how bacterial infections are treated.